Photo:

Lynne Cox

My CV

Education:

King’s High School, Warwick and Cambridge University

Qualifications:

MA (Hons) Natural Sciences; PhD

Work History:

Cambridge, Dundee, Oxford

Current Job:

University Lecturer in Biochemistry and Tutorial Fellow in Biochemistry

Employer:

University of Oxford and Oriel College, Oxford

Me and my work

My lab works on understanding the molecular basis of ageing.

We use a range of model systems to study what happens as cells and organisms age. In particular, we are very interested in the role of a protein called WRN that helps to stop cells ageing prematurely. We are studying the effect of mutating this gene in worms and flies, to explain why people with a mutation in WRN show many of the signs of normal ageing. We also have a long term project to age human cells in the lab and measure biochemical changes with age.

My Typical Day

I try to fit in experiments around teaching, admin, meetings, seminars and reading lots of scientific papers.

I run my own experiments looking at human cell ageing and collaborate with colleagues on fly and worm ageing. I also teach undergraduate students and supervise graduates. and research staff. There is no such thing as a typical day – they are all very different from each other but very busy and good fun.

My Interview

How would you describe yourself in 3 words?

Fascinated by life

What living thing amazes you the most?

Oddly, bacteriophage lambda, as it has an amazing life cycle with so few genes

What is the most fun thing you've done?

I spent a summer exploding things for British Gas – it was amazing

Were you ever in trouble in at school?

I accidentally left footprints on the ceiling once….

If you weren't a scientist, what would you be?

I can’t think of anything that could be as interesting

What's the best thing you've done as a scientist?

Experimentally, it could be showing a DNA replication defect in Werner syndrome; teaching is really satisfying too, especially when your students become great scientists

Who or what inspired you to become a scientist?

Marie Curie – I read about her when I was 10 and wanted to be like her.

What would your superpower be?

Flight

If I could change one thing about the world...

I would resolve the problems we have caused by global warming

My favourite CHRISTMAS LECTURE memory is:

Alison cartwheeling at the start of lecture 3

The most Fantastic thing about Life is:

It’s ALL amazing -hard to choose the most fantastic bit, but adaptability comes high on my list.

Other stuff

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